Heterogeneity within medullary-type TCRαβ+CD3+CD4–CD8+ thymocytes in normal mouse thymus

heterogeneity within the orientalist discourse: representation of the orient in womens travelogues and mens paintings

from 1950s onward, new theories and critical approaches burgeoned across humanities. these theories were context-oriented; as a result, the analysis of discursive practices gained significance. thus, social, political, historical and cultural discourses that have been hitherto marginalized and considered inferior to literary texts, were introduced as important texts to be analyzed by critics. o...

The late stage of T cell development within mouse thymus.

After positive selection and lineage commitment, the TCR alphabeta+ CD4/CD8 SP medullary thymocytes migrate into and reside in thymic medulla, where they undergo an ordered program of late stage of T cell functional maturation and negative selection to delete self-reactive clones by apoptosis. Accomplishment of this final differentiation pathway, a physiological T cell repertoire is formed: T c...

Generation of CD3+CD8low thymocytes in the HIV type 1-infected thymus.

Infection with the HIV type 1 (HIV-1) can result both in depletion of CD4(+) T cells and in the generation of dysfunctional CD8(+) T cells. In HIV-1-infected children, repopulation of the peripheral T cell pool is mediated by the thymus, which is itself susceptible to HIV-1 infection. Previous work has shown that MHC class I (MHC I) molecules are strongly up-regulated as result of IFN-alpha sec...

Intraepithelial Lymphocytes and Thymocytes Antigen Tetramers to Normal Intestinal The Binding of Thymus Leukemia (TL)

Generation of CD3 CD8 Thymocytes in the HIV Type 1-Infected Thymus